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Real world data

Whilst primary data collection in the form of clinical trials is still considered the gold standard for answering healthcare relating questions, there is a recognition that this is not always feasible, ethical, or value for money. Cedar has expertise in projects which use real world data (or routinely-collected data) collected through registries or data linkage.

Cedar's real world data studies

Value in Health

Cedar is an integral part of the national Value in Health programme. We provide analytical and evaluation capacity.


ROPE registry project to determine the safety and efficacy of prostate artery embolisation (PAE) for lower urinary tract symptoms secondary to benign prostatic enlargement (LUTS BPE).


This prospective, single-arm, observational, service evaluation study on Selective internal radiotherapy (SIRT) in patients with advanced liver metastases in 10 NHS hospitals in England. This was part of NHS England's Commissioning through Evaluation (CTE) programme. 

HERO (Hypoglycaemic Episode Resource Outcomes)

The project used linked healthcare records obtained from the SAIL databank in order to determine the number of hypoglycaemic episodes in patients with type 1 diabetes. These data were combined with type 1 registration data from the National Diabetes Audit in order to determine the cumulative incidence of hypoglycaemia in type 1 diabetes.

CALON (Cardiac Ablation: Linking Outcomes for NICE)

CALON used linked patient records from different sources to obtain evidence about how well cardiac ablation procedures work, and how safe they are.